Contact info

ncastell at cs dot ucsd dot edu

Dept. of Computer Science and Engineering
9500 Gilman Drive, Mail Code 0404
La Jolla, CA 92093
EBU3b Office 4230

Relevant Links

Mass Spectrometry Journal Club blog

IGERT Journal Club schedule

Open research project list wiki

Digital Proteomics LLC

About me

I am a recent Ph.D. graduate from the University of California-San Diego in Computer Science. Currently, I am the Chief Technology Officer at Digital Proteomics, LLC. At UCSD, my advisor was Dr. Vineet Bafna and my co-advisor was Dr. Steve Briggs. My thesis focused on applications of peptide mass spectrometry, particularly proteogenomics. Our group page is here. I was previously supported by the IGERT Plant Systems Biology Training Grant


Castellana, NE, Lushnikov, A, Rotkiewicz, P, Sefcovic, N, Pevzner, PA, Godzik, A and Vyatkina, K (2012). MORPH-PRO: A Novel Algorithm and Web Server for Protein Morphing. To appear at WABI 2012.

Castellana, NE, McCutcheon, K, Pham, VC, Harden, K, Nguyen, A, Young, J, Adams, C, Schroeder, K, Arnott, D, Bafna, V, Grogan, JL, Lill, JR (2011). Resurrection of a clinical antibody: template proteogenomic de novo proteomic sequencing and reverse engineering of an anti-lymphotoxin-alpha antibody. Proteomics, 11, 3:395-405.

NE Castellana, V Bafna. (2010). Proteogenomics to discover the full content of genomes: a computational perspective. J. Proteomics, 73, 11:2124-35.

NE Castellana, V Pham, D Arnott, JR Lill, V Bafna. (2010). Template Proteogenomics: sequencing whole proteins using an imperfect database. Mol. Cell. Proteomics, 9, 6:1260-70.

NE Castellana, SH Payne Z Shen M Stanke V Bafna and SP Briggs. (2008). Discovery and revision of Arabidopsis genes by proteogenomics. PNAS, 105, 52:21034-38.

N. Castellana, K. Dhamdhere, S. Sridhar, and R. Schwartz. (2006). Relaxing Haplotype Block Models for Association Testing. Proc. of the Pacific Symposium on Biocomputing.


Ph.D. in Computer Science, University of California-San Diego 2006-2012
M.S. in Computer Science, University of California-San Diego 2006-2009
B.S. in Computer Science, Carnegie Mellon University 2002-2006