About me
I am a recent Ph.D. graduate from the University of California-San Diego in Computer Science. Currently, I am the Chief Technology Officer at Digital Proteomics, LLC. At UCSD, my advisor was Dr. Vineet Bafna and my co-advisor was Dr. Steve Briggs. My thesis focused on applications of peptide mass spectrometry, particularly proteogenomics. Our group page is here. I was previously supported by the IGERT Plant Systems Biology Training Grant
Publications
Castellana, NE, Lushnikov, A, Rotkiewicz, P, Sefcovic, N, Pevzner, PA, Godzik, A and Vyatkina, K (2012). MORPH-PRO: A Novel Algorithm and Web Server for Protein Morphing. To appear at WABI 2012.
Castellana, NE, McCutcheon, K, Pham, VC, Harden, K, Nguyen, A, Young, J, Adams, C, Schroeder, K, Arnott, D, Bafna, V,
Grogan, JL, Lill, JR (2011). Resurrection of a clinical antibody: template proteogenomic de novo proteomic sequencing
and reverse engineering of an anti-lymphotoxin-alpha antibody. Proteomics, 11, 3:395-405.
Pubmed
NE Castellana, V Bafna. (2010). Proteogenomics to discover the full content of genomes: a computational perspective. J.
Proteomics, 73, 11:2124-35.
Pubmed
NE Castellana, V Pham, D Arnott, JR Lill, V Bafna. (2010). Template Proteogenomics: sequencing whole proteins using an
imperfect database. Mol. Cell. Proteomics, 9, 6:1260-70.
Pubmed
NE Castellana, SH Payne Z Shen M Stanke V Bafna and SP Briggs. (2008). Discovery and revision of Arabidopsis genes
by proteogenomics. PNAS, 105, 52:21034-38.
Pubmed
N. Castellana, K. Dhamdhere, S. Sridhar, and R. Schwartz. (2006). Relaxing Haplotype Block Models for Association
Testing. Proc. of the Pacific Symposium on Biocomputing.
PubMed
Education
Ph.D. in Computer Science, University of California-San Diego 2006-2012
M.S. in Computer Science, University of California-San Diego 2006-2009
B.S. in Computer Science, Carnegie Mellon University 2002-2006